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[FP-FR-27] Uveitis Diagnosis & Treatment
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Apr 04 (Fri)
13:30 - 15:00
Room 13 - Tokyo International Forum 4F G402
Uveitis, Intraocular Inflammation
Chair)Bahram Bodaghi、Chair)Manabu Mochizuki


Duration 5min, Q&A 3min

Multimodal Imaging for the Diagnosis of Acute Vogt-Koyanagi-Harada Disease without Clinically Evident Exudative Retinal Detachment

Moncef Khairallah
Moncef Khairallah Sonia Attia Sana Khochtali Dhiaeddine Ammous Sonia Zaouali

To assess the role of multimodal imaging in the diagnosis of acute Vogt-Koyanagi-Harada (VKH) disease without clinically evident exudative retinal detachment (ERD).

Thirty six eyes of 18 consecutive patients (12 females and 6 males) aged between 23 and 60 years (Mean 39 years).

All patients underwent clinical examination, color fundus photography, optical coherence tomography (OCT), fluorescein angiography (FA), indocyanine green angiography (ICGA), and B ultrasonography.

Results and Conclusion
Of 36 eyes, 22 (61%) had panuveitis and 14 (39%) had posterior uveitis. Main fundus findings included optic disc swelling in 30 eyes (83%) and choroidal / retinal folds in 20 eyes (55%). OCT findings included multifocal folds of retinal pigment epithelium in 23 eyes (64%), a shallow, limited ERD in 18 eyes (50%). FA findings included delayed choroidal perfusion in at least one eye of all patients (100%), hyperfluorescent pinpoints without obvious subretinal pooling in 21 eyes (58%), and optic disc hyperfluorescence in 35 eyes (97%). ICGA findings included delayed choroidal perfusion in 24 eyes (67%), decrease in the number of large choroidal vessels in 36 eyes (100%), fuzzy choroidal vessels in 35 eyes (97%), and hypofluorescent dark dots during the intermediate phase either becoming isofluorescent or remaining hypofluorescent in the late phase in 28 eyes (78%). B ultrasonography showed diffuse, low to medium reflective choroidal thickening in all eyes (100%).
A careful clinical examination combined with multimodal imaging approach, including OCT, FA, ICGA, and ultrasonography is mandatory for the early, definite diagnosis of acute VKH disease without clinically evident ERD.

[ Keyword ]
Vogt Koyanagi Harada disease / Exudative retinal detachment / Multimodal imaging

[ Conflict of Interest ]

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