演題

RS3-143-13-6

高齢者膵癌に対する膵切除の短期及び長期の治療成績の検討

[演者] 青山 徹:1,2
[著者] 山本 直人:1,2, 神谷 真梨子:1,2, 佐藤 勉:1, 湯川 寛夫:1, 大島 貴:1, 吉川 貴己:1, 利野 靖:1, 益田 宗孝:1, 森永 聡一郎:2
1:横浜市立大学附属病院 一般外科, 2:神奈川県立がんセンター 消化器外科

Background: The short- and long-term outcomes of pancreatic resection for pancreatic adenocarcinoma have not been fully evaluated in elderly patients. Methods: This retrospective study selected patients who underwent curative surgery for pancreatic cancer at our institution. Patients were categorized into two groups; non-elderly patients (age <75 years: group A) and elderly patients (age ≥75 years: group B). The surgical morbidity, surgical mortality, overall survival (OS), and recurrence-free survival (RFS) rates in the two groups were compared. Results: A total of 221 patients were evaluated in the study. The overall complication rates were 44.8% in Group A and 52.6% in Group B. Surgical mortality was observed in 2 patients due to an abdominal abscess and cardiovascular disease in Group A (1.1%) and in 1 patient due to postoperative bleeding in Group B (2.6%). There were no significant differences (p=0.379 and p=0.456, respectively). Furthermore, the 5-year OS and RFS rates were similar between the elderly patients and non-elderly patients (18.55 vs. 20.2%, p=0.946 and 13.1% vs. 16.0%, p=0.829, respectively). Conclusions: The short-term outcomes and long-term survival after pancreatic resection for pancreatic adenocarcinoma were almost equal in the elderly and the non-elderly patients in this study. Therefore, it is unnecessary to avoid pancreatic resection for pancreatic adenocarcinoma in elderly patients may be candidates simply because of their age.
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