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RC-09-138

Neural correlates of cognitive inhibition and attentional bias in a non-clinical sample of adolescents

[Speaker] Tirado Santiago, Giovanni:1
[Co-author] Algaze Beato, Antonio:1, Rosado Santiago, Coral:1, Rodriguez Corcelles, Lydia C:1, Quiñones Camacho, Laura E:1, López Valentín, Cybelle M:1
1:University of Puerto Rico (United States of America)

Attentional bias to negative information underlies vulnerability for mood and anxiety symptoms. The aim of this study was to assess in adolescents the neural correlates of cognitive inhibition and attentional biases during an emotional Stroop task using BOLD fMRI at 3T. Seven participants age 14.28 (SD=1.17; 3 females) were assessed on behavioral and psychological domains to rule out any serious disorder. Afterwards participants completed the task during an fMRI session. Participants who were presented with words in one of four colors had to press a button to state the words' color. A mixed-effects analysis in FSL demonstrated that the left IFG, middle temporal gyrus and paracingulate gyrus presented a significantly higher BOLD response when processing neutral vs. negative words (Z=2.3, p<.05). Results show that in a non-clinical sample, regions associated with cognitive inhibition showed more activation in a task with emotional stimuli and large attentional demands.
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