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Poster
PS28A-03-265

Impact of different initial epinephrine treatment time points on the neurologic functions of children with traumatic out-of-hospital cardiac arrest

[Speaker] Lin, Yan Ren:1
1:Department of Emergency Medicine, Changhua Christian Hospital (Taiwan)

Background: To analyze the early post-resuscitative hemodynamics, survival and neurologic outcome according to different time points of first epinephrine treatment among children with traumatic OHCA.
Methods: Information on 388 children who were treated with epinephrine for traumatic OHCA during the study period (2003-2012). The post-resuscitative hemodynamic features, survival and neurologic outcome according to different time points of first epinephrine treatment (<15, 15 to 30 and >30 minutes after collapse) were analyzed.
Results: Among 165 children achieved sustained return of spontaneous circulation (ROSC), 12 (3.1%) had good neurologic outcomes. Early treating epinephrine (<15 minutes after collapse) increased the post-resuscitative cardiac output only in the first 30 minutes but ultimately impaired end-organ perfusion (all p<0.05). Early epinephrine increased the chance of achieving sustained ROSC but did not increase the rates of survival and neurologic outcome.
Conclusions: The rates of survival and good neurologic outcome were not significantly increased by early epinephrine administration.
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