Program

Poster
PS27A-06-334

Brain-based Lifespan Trajectory of Social Cognition

[Speaker] Zhixiong, Yan:1,2
[Co-author] Xinian, Zuo:1,2
1:Guangxi Teachers Education University (China (People's Republic of China)), 2:Institute of Psychology, Chinese Academy of Sciences (China (People's Republic of China))

We, here, aim to examine age-related changes of large-scale brain networks in social cognition. We collect 44 cortical regions of interest (ROIs) as modularity (termed as network of theory of mind (ToM), empathy and moral cognition later) from a meta-analysis (Bzdok et al., 2012). Using public fMRI imaging data (N = 627, ages 6-85 years old), we calculate the network-level functional connectivity (NFC) and model its trajectories. The results show that the overall social cognition, ToM, and empathy networks present in a quadric-convex trajectory with peak ages around 33-years-old, while the moral cognition network emerges as a linearly decrease trend. All inter-networks (moral cognition and ToM, moral cognition and empathy, ToM and empathy networks), present inverted U-shape trajectories with plateau age from 30-35 approximately. We investigated the lifespan trajectories of social cognition networks, which indicate intrinsic brain architecture associated with the age-related dynamics cross the lifespan.
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