Is age at symptom onset associated with inhibitory deficits in adults with obsessive-compulsive disorder?

[Speaker] Lei, Hui:1
[Co-author] Zhang, Xiaocui:2, Zhu, Xiongzhao:2
1:College of Education, Hunan Agriculture University, Changsha, China (China (People's Republic of China)), 2:Medical Psychological Institute, Second Xiangya Hospital, Central South University, Changsha, China (China (People's Republic of China))

The aim of this study was to examine the association between age at symptom onset and inhibitory deficits in adults with OCD. We compared the performance of 53 adult patients with early-onset OCD, 47 of adult patients with later-onset OCD, and 55 healthy controls on the emotional Stroop task and stop-signal task. Both patient groups showed larger negative interference scores than controls in the emotional Stroop task. For the stop-signal task, stop-signal reaction time was longer in both OCD groups compared to control group. No differences were found between the two OCD groups. Our findings support the existence of inhibitory deficits in patients with early-onset OCD and later-onset OCD. Onset age is not associated with inhibitory control performance in adults patients with OCD, thus such dysfunction appears to be a consistent feature of OCD in adults, regardless of age at initial symptom onset.
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