Presentation Information

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[FP-SA-43] Ocular Imaging
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Day
Apr 05 (Sat)
Time
15:30 - 17:00
Room
Room 13 - Tokyo International Forum 4F G402
Topic
Ocular Imaging
Chair/Coordinator
Chair)Yoko Miura、Chair)Dirk-Uwe Bartsch
 
 
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FP-SA-43-4

Duration 5min, Q&A 3min

Fundus Autofluorescence Imaging of Acute Zonal Occult Outer Retinopathy

【Speaker】
Libin Jiang
【Author】
Libin Jiang Qian Wang Qisheng You


Objective/Purpose
Purpose: To investigate changes of fundus autofluorescence ( FAF ) in eyes with acute zonal occult outer retinopathy ( AZOOR ) and relationships between appearance of FAF and optical coherence tomography (OCT), Humphrey visual field (HVF), and multifocal electroretinogram (mfERG)

Materials/Patients
Methods: Retrospective analysis of the characters of FAF manifestations and the relationships between FAF findings and clinical features in a series of patients with AZOOR.

Methods
Methods: Retrospective analysis of the characters of FAF manifestations and the relationships between FAF findings and clinical features in a series of patients with AZOOR.

Results and Conclusion
Result: There were 20 eyes of 20 patients (16 women, 80.0%; 4 men, 20.0%; mean age 32.14, youngest 9, oldest 57) diagnosed as AZOOR according to the diagnosis criterion proposed by Gass. Unilateral involvement was found in all patients. At first presentation, the best corrected visual acuity ranged from 2/200 to 24/20. Anterior segment examinations were normal, except for the presence of relative afferent papillary defect in 9 eyes (45.0%). OCT revealed an absent inner segment/outer segment (IS/OS) boundary in retina corresponding to the dysfunction areas shown in mfERG and HVF. FAF abnormality was detected in 18 eyes (90.0%). FAF abnormality demonstrated either hyperautofluorescence or hypoautofluorescence, and had varied shapes. But in most patients, FAF clearly showed the boundary between the normal and abnormal retina, and this was correspondent with the boundary revealed by OCT, mfERG and HVF.
Conclusion: FAF abnormalities were detected in most AZOOR eyes and some abnormalities were found corresponding to the abnormality in retina revealed by OCT, HVF and mfERG. We thus suggest that FAF might be used to diagnose AZOOR.

[ Keyword ]
Acute zonal occult outer retinopathy / Fundus autofluorescence / Optical coherence tomography / Multifocal electroretinogram

[ Conflict of Interest ]
No

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