Duration 5min, Q&A 3min
Eyelid Malignancies in Bangladesh: A Clinico-Pathologic Study
Purpose: To characterize the nature, pattern and management strategies of different types of eyelid malignancies in Bangladesh
Patients: Observational multicentre case series study was done from 2008 to 2012 (five years). Patients presented with eyelid mass or ulcer or thick eyelid margin were clinically evaluated by meticulous history taking, assessment of the lesion, ocular and physical examination with old photographs. differential distribution of variables observed in this study.
All clinically diagnosed patients with eyelid malignancy underwent either excision biopsy with 4 mm normal tissue or frozen section biopsy. Experienced pathologist reported all cases. Management strategy was setup on location, types of lesion, orbital involvement, metastasis to lymph node and distant organ. Statistical analysis was used to assess the
Results and Conclusion
Results: We evaluated 164 patients those who were presenting eyelid malignancies. Among them, one patients presented both (right and left) side eyelid malignancy. Analysis revealed Sebaceous gland carcinoma (SGC) was 67 cases (40.8%), Basal cell carcinoma (BCC) was 65 cases (39.6%), Squamous cell carcinoma (SCC) was 29 cases (17.6%), Malignant melanoma (MM) was 02 cases (1.2%) and Apocrine adenocarcinoma (AA) was 01 case (0.6%). The frequency of SGC was little higher than BCC. Male patients were 92 (56%) and female patients were 72 (44%). The mean age was 56.31, 60.72, 64.12 and 52.50 in SGC, BCC, SCC and MM respectively. Frozen section was done in 72 cases (44%). Lower eyelid was more involved in BCC (70.7%) and upper eyelid was more involved in SGC (76%). Orbit was involved in 06 cases (3.6%). Invasion to periocular structures was involved in 1.6% cases and metastasis were in 1.2% cases. Eyelid reconstruction was done by direct closure in 48 cases (29.3%), Tenzel and reverse tenzel in 30 cases (18.3%), Triangular flap in 12 cases (7.3%), Tarso-conjuctival rotational flap in 06 (3.6%) cases, Cutler beared procedure in 18 (11%), Hughes procedure in 20 cases (12%), Mustard check rotational flap in 05 cases (3%), Skin graft in 16 cases (9.8%), Z plasty and skin graft in 03 cases (2%), Exenteration in 06 cases (3.7%).
Conclusion: Sebaceous gland carcinoma of the eyelid is highest frequency in Bangladesh. Early diagnosis and prompt management provides minimum invasive procedure, completely cure the lesion, salvage the globe and prevents metastasis.
[ Keyword ]
Sebaceous gland carcinoma, Basal cell carcinoma, Squamous cell carcinoma
[ Conflict of Interest ]