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[FP-FR-26] Update on Glaucoma Investigations (Non-Imaging)
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Apr 04 (Fri)
10:30 - 12:00
Room 13 - Tokyo International Forum 4F G402
Chair)Naoki Tojo、Chair)Ted Maddess、Chair)Christoph Hirneiss


Duration 5min, Q&A 3min

Comparison of Fluctuations of Intraocular Pressure before and after Cataract Surgery in Primary Angle Closure Glaucoma Patients

Naoki Tojo
Naoki Tojo

It is well known that cataract extraction can reduced intraocular pressure (IOP) in eyes with primary angle closure glaucoma (PACG). To examine changes in preoperative and postoperative IOP fluctuations we performed phacoemulsification and intraocular lens implantation (PEA+IOL) for PACG patients and measured IOP fluctuations using a contact lens sensor (CLS) of Triggerfish.

Ten patients diagnosed with PACG at Toyama University Hospital were enrolled in this study.

10 patients with PACG underwent PEA+IOL. Twenty four hour continuous IOP was measured in each eye before and 3months after the PEA+IOL. Changes in corneal thickness and corneal curvature were also measured with an anterior segment optical coherence tomography.

Results and Conclusion
The mean IOP was 14.7 ± 1.5 mmHg before PEA+IOL. The mean IOP at 3 months after PEA+IOL was significantly decreased to 11.2±2.2 mmHg (p=0.002). The range of IOP fluctuations over 24 hours was not significantly changed between before and after PEA+IOL (p=0.49). Although the range of IOP fluctuations during the diurnal periods was not significantly changed (p=0.92), the range of IOP fluctuations during the nocturnal periods was significantly decreased from 246 ± 61 mVeq before SLT to 179 ± 64 mVeq (p=0.02). With respect to corneal changes, the steeper and flatter meridian, and central corneal thickness showed no significant difference between before and after the CLS use.
This study showed that the cataract surgery (PEA+IOL) significantly lowered IOP and IOP fluctuations during the nocturnal periods in PACG patients. The PEA+IOL might contribute to prevent the progression of PACG.

[ Keyword ]
primary angle closure glaucoma / intraocular pressure / PEA+IOL / fluctuation

[ Conflict of Interest ]

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