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[FP-FR-26] Update on Glaucoma Investigations (Non-Imaging)
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Day
Apr 04 (Fri)
Time
10:30 - 12:00
Room
Room 13 - Tokyo International Forum 4F G402
Topic
Glaucoma
Chair/Coordinator
Chair)Naoki Tojo、Chair)Ted Maddess、Chair)Christoph Hirneiss
 
 
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FP-FR-26-6

Duration 5min, Q&A 3min

Evaluation of Acquired Color Vision Defects of Glaucoma Using Cone Contrast Test

【Speaker】
Yuichi Niwa
【Author】
Yuichi Niwa Sanae Muraki Masahito Ohji


Objective/Purpose
To evaluate a new computer-based cone contrast test (CCT) as a tool for detection of glaucoma

Materials/Patients
Twenty-seven eyes of 27 patients with primary open angle glaucoma or normal tension glaucoma and 27 eyes of 27 normal subjects were included in this study.

Methods
All eyes were measured L, M and S cone contrast scores (L CCT, M CCT, and S CCT) using CCT. Glaucomatous eyes underwent visual field tests (VF) with program 30-2 of the Humphrey Field Analyzer (Carl Zeiss Meditecs, Dublin, CA) and macular scanning using the Cirrus HD-OCT (Carl Zeiss Meditecs, Dublin, CA).The ganglion cell analysis algorithm was used to measure macular ganglion cell-inner plexiform layer (GCIPL)

Results and Conclusion
Sixteen glaucomatous (59%) of 27 eyes showed reduced CCT scores of one or more cones, 4 eyes (15%) showed reduced L CCT. 11 eyes (41%) showed reduced M CCT. 9 eyes showed reduced S CCT. There were significant differences in the median M CCT (85 vs. 90) and S CCT (95 vs. 100) between the groups (p<0.05), however, did not reach statistical significance in L CCT (P=0.065). M CCT and S CCT were significantly correlated with mean deviation MD(r=0.47, p<0.05; r=0.44, p<0.05), and GCIPL (r=0.70, p<0.0001; r=0.57, p<0.01).
CCT has a potential to be useful tool to quantify acquired color vision defects and to detect progression of glaucoma.

[ Keyword ]
Cone contrast test / Acuired color vision defect / Glaucoma

[ Conflict of Interest ]
No

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