演題詳細

ポスター / Poster

ポスター 49 (Poster 49) :ウイルス感染症

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日程
2013年10月11日(金)
時間
16:50 - 17:50
会場
ポスター会場 / Poster (ロイトン札幌 3F エメラルドABCD)
座長・司会
古川 雄祐 (Yusuke Furukawa):1
1:自治医科大学分子病態治療研究センター 幹細胞制御研究部
 
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The seroprevalence of HTLV-1 in patients with autoimmune thyroid diseases

演題番号 : PS-1-377

北中 明 (Akira Kitanaka):1、栗林 忠信 (Tadanobu Kuribayashi):2、楠元 寿典 (Kazunori Kusumoto):2、久冨木 庸子 (Yoko Kubuki):1、日高 智徳 (Tomonori Hidaka):1、幣 光太郎 (Kotaro Shide):1、亀田 拓郎 (Takuro Kameda):1、関根 雅明 (Masaaki Sekine):1、上運天 綾子 (Ayako Kamiunten):1、鶴田 来美 (Kurumi Tsuruta):3、藤井 良宜 (Yoshinori Fujii):4、松岡 均 (Hitoshi Matsuoka):2、下田 和哉 (Kazuya Shimoda):1

1:Gastroenterology and Hematology, Faculty of Medicine, University of Miyazaki, Japan、2:Koga General Hospital, Miyazaki, Japan、3:School of Nursing, University of Miyazaki, Miyazaki, Japan、4:Faculty of Education and Culture, University of Miyazaki, Miyazaki, Japan

 

Background: HTLV-1 has been reported in association with autoimmune thyroid disease. Previous reports were mainly based on studies of small numbers of patients.
Objective: To evaliuate the prevalence of HTLV-I seropositivity among patients with autoimmune thyroid disease.
Results: The seroprevalence of HTLV-1 in patients with thyroid diseases and the estimated prevalence calculated after adjustment for age were as follows: 1 (2.4%) vs 2.0 (4.8%) (p = 0.48) for men with chronic thyroiditis (n = 42), 26 (5.6%) vs 26.3 (5.6%) (p = 0.95) for women with chronic thyroiditis (n = 468), 0 (0%) vs 2.4 (3.4%) (p = 0.12) for men with Graves' disease (n = 71), 19 (4.9%) vs 14.3 (3.7%) (p = 0.22) for women with Graves' disease (n = 386), 6 (6.7%) vs 4.2 (4.7%) (p = 0.38) for men with non-autoimmune thyroid disease (n = 89), and 15 (4.1%) vs 21.7 (6.0%) (p = 0.15) for women with non-autoimmune thyroid disease (n = 364). The measurement of proviral load of HTLV-I in peripheral blood mononuclear cells from HTLV-I-infected patients with chronic thyroiditis, Graves' disease, or non-autoimmune thyroid disease revealed no significant difference between three groups.
Conclusion: Contrary to previously described observations, there was no significant statistical difference in the prevalence of HTLV-1 seropositivity between patients with autoimmune thyroid disease and normal population.

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