演題詳細

一般口演 / Oral Session

一般口演 74 (Oral Session 74) :貧血の臨床

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日程
2013年10月13日(日)
時間
08:45 - 09:45
会場
第4会場 / Room No.4 (さっぽろ芸文館 3F 黎明)
座長・司会
亀岡 淳一 (Junichi Kameoka):1
1:東北大学 血液・免疫病学分野
 
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Cross-sectional study of the relationships between erythropoiesis and nutrition, adiponectin

演題番号 : OS-3-12

高野 桂 (Kei Kohno):1、成松 宏人 (Hiroto Narimatsu):2、塩野 洋介 (Yosuke Shiono):1、鈴木 郁子 (Ikuko Suzuki):1、加藤 裕一 (Yuichi Kato):1、加藤 丈夫 (Takeo Kato):1

1:Department of Hematology, Yamagata University, Japan、2:Department of Public Health, Yamagata University, Japan

 

Although erythroid abnormalities (anemia and polycythemia) are commonly observed pathological conditions, not much information about borderline abnormalities is available. In the present study, a cross-sectional study to analyze the relationships between erythropoiesis and nutrition, physical features, and laboratory test findings was conducted in middle-aged and older men and women. The study included 3519 Japanese people (1579 men and 1940 women), age 40 years and over, and their physical measurements, blood tests, nutrition survey, and physical activity status were examined. Analysis of variance showed that the group with a tendency to anemia was older, had a lower body mass index and diastolic blood pressure, and higher adiponectin levels and renal function. Multiple regression analysis showed that adiponectin, triglycerides, and total protein were common factors that affected erythropoiesis in both men and women. Hepatic, renal, and cardiac functions were also factors involved in erythropoiesis in men and in postmenopausal women. In addition, nutrient factors such as alcohol, vitamins, and carbohydrates were also significantly involved in erythropoiesis in men, but there were no significant nutrient factors involved in erythropoiesis in either premenopausal or postmenopausal women. This study showed that factors that influence erythropoiesis differ among men, premenopausal women, and postmenopausal women, and it suggested that appropriately modifying erythropoiesis management for each group of people is essential.

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