演題情報

Symposium

開催回
第60回・2015年・横浜
 

Frail dialysis population: growing burden for dialysis community

演題番号 : GI-10-4-1

Kirsten L. Johansen:1

1:University of California, San Francisco, USA

 

The age of the dialysis population has increased throughout the world over the last several decades. In 2011, the mean age of new dialysis patients in Japan was 67.8 years, and the mean age of the whole Japanese dialysis population was 66.6 years. Along with the increase in age has come a greater burden of comorbid conditions. These factors contribute to frailty in the dialysis population, but the burden of frailty is considerably higher than would be expected based on age and diabetes alone. There are several methods for classifying patients as frail, and depending on the definition of frailty used, its prevalence ranges from 30 to 73% among patients on hemodialysis. Although frailty is more common among older patients, it is not limited to the elderly. Patients with higher fat mass and lower intracellular water per kg of body weight are more likely to be frail. Frailty is associated with higher risk of subsequent falls and fractures and with higher mortality. Nevertheless, some patients do recover from frailty, and investigation is underway to identify factors associated with the development of and recovery from frailty as well as ways to address it.

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