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≪Organizer Abstract≫
Major depressive disorder (MDD) is characterized by a pervasive and persistent low mood that is accompanied by low self-esteem and by a loss of interest or pleasure in normally enjoyable activities. MDD is a common, complex and often lifelong mental disorder, which has worldwide public health importance. Despite the development of a lot of pharmacological and psychological interventions, many individuals with MDD fail to respond to treatment and are plagued by relapse. It is therefore imperative that we continue exploring the underlying nature of MDD, as a greater understanding of vulnerability and phenomenological models will help inform future intervention research efforts. This symposium will discuss recent strides in better elucidating MDD. In particular, we will highlight innovative studies from the perspective of neuroimaging, epigenetics and machine learning.
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