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≪Organizer Abstract≫
This symposium addresses behavioral and neurobiological effects of insulin and oxytocin in humans, also considering differential variables, i.e., sex (hormone)-related differences and genetic variations. The studies mainly used the intranasal route to administer insulin and oxytocin into the brain. Ursula Stockhorst (Osnabrueck, Germany) and Manfred Hallschmid (Tuebingen, Germany) examine the effects of intranasal insulin on hormones and glucose metabolism, on eating behavior and body- weight in males and females. Moreover, nutrition-induced effects on olfaction are addressed (Stockhorst), assuming to reflect insulin-mediated actions in brain olfactory areas. Oxytocin also has a broad action profile. First, we learn about its role in food-intake, body-weight and metabolism (Hallschmid). Peter Kirsch (Mannheim, Germany) addresses the impact of the oxytocin system and related polymorphisms on social behavior and its neurobiological correlates. Richard Ebstein (Singapore) reveals a new action of an oxytocin-receptor genotype which buffers the impact of impatience on cellular aging in young females.
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